Merck, SAB5702649-100UL, Anti-APPL1 Antibody, clone 4M5X9, Rabbit Monoclonal

General description
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human APPL11 (Q9UKG1).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB