Merck, SAB5702865-100UL, Anti-EGFR (L858R) Antibody, clone 1J5C6, Rabbit Monoclonal

General description
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 800-900 of human EGFR (L858R) (P00533).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC