Merck, SAB5702894-100UL, Anti-GRK3 Antibody, clone 10O6S3, Rabbit Monoclonal

General description
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 589-688 of human GRK3 (P35626).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB