Merck, SAB5703027-100UL, Anti-ADRA1A Antibody, clone 4G10W8, Rabbit Monoclonal

General description
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human ADRA1A (P35348).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB