Merck, SBPVR1-9RXN, SB PREDIVEZ™ Reagent Kit for MDR1/P-gp

General description
SOLVO Biotechnology offers ready-to-use assay kits for efflux and uptake transporters. SOLVO′s PREDIVEZ Vesicular Transport Assay Kits are suitable for efflux transporter inhibition studies. The kits are designed to test the inhibitory effect of one or more test compounds on the vesicular transport of a probe substrate. In most cases a fluorescent probe substrate is included. Kits contain all reagents and solutions necessary to conduct the drug-transporter interaction assay of need.
Application
The PREDIVEZ Vesicular Transport Kit is a simple and powerful tool to investigate drug transporter interactions. It provides information on any interaction between the ABC transporter and the drug candidate that would affect the transport of the fluorescent or radiolabeled or cold.

PREDIVEZ vesicular transport kits contains buffers, probe substrate, and reference inhibitors needed to run vesicular transport assays (sufficient for 300 wells/kit –equivalent to existing 9-cpd PV kits). Assay protocol, calculation template, and example data file available on SOLVO website.

Transport membranes and control membranes are sold separately. This PREDIVEZ vesicular transport kit requires the control membrane SB K CTRL part number SBCT01-1EA and can be used with the below transporter membranes:

SB-MDR1-K-VT MDR1 human membrane vesicles part number SBVT01-1EA
Legal Information
PREDIVEZ is a trademark of Solvo Biotechnology