Merck, SBR00068-10ML, Streptomycin

Name: Streptomycin
Brand: Merck
SKU: SBR00068-10ML

Size:10 mL, Ready Made Solution, 100 mg/mL in water

Catalog Number: SBR00068-10ML

Pricing

Send an RFQ.

View RFQ List

Category

Antibiotics & Antimycotics

Pack Size10 mL

TagsChemistry & Biochemicals Biochemicals Antibiotics

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Chemical structure: aminoglycoside
Application
Streptomycin is used to study mechanisms of streptomycin resistance and is often used together with penicillin and other agents to inhibit bacterial contamination in cell culture applications. It is recommended for use in molecular biology applications at 25-50 μg/mL, in cell culture applications at 100 mg/L and in embryo culture at 50 mg/L.
Biochem/physiol Actions
Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.

Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.

Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Preparation Note

Streptomycin ready made solution contains 100 mg/mL streptomycin sulfate in water.
Streptomycin: sulfate salt ratio is 1:1.5.

Specifications

General

UNSPSC Code	51281624
NACRES	NA.76
SMILES string	[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.N([C@@H]4[C@@H](O[C@H]([C@@H]([C@H]4O)O)CO)O[C@H]5[C@@H](O[C@H]([C@]5(O)C=O)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H]([C@@H]6O)O)N=C(N)N)O)N=C(N)N)C.N([C@@H]1[C@@H](O[C@H]([C@@H]([C@H]1O)O)CO)O[C@H]2[C@@H](O[C@H]([
InChI key	QTENRWWVYAAPBI-YZTFXSNBSA-N
InChI	1S/2C21H39N7O12.3H2O4S/c21-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;31-5(2,3)4/h24-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-
Quality Level	200
form	liquid
specific activity	(Antibacterial)
concentration	100 mg/mL in water
antibiotic activity spectrum	Gram-negative bacteria
application(s)	advanced drug delivery
mode of action	protein synthesis \| interferes
storage temp.	−20°C

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.

Merck, SBR00068-10ML, Streptomycin

Send an RFQ.

General

Notice

More from Merck.

CombiTitrant 5

SUPELCOSIL™ ABZ+Plus HPLC Column

SUPELCOSIL™ LC-CN HPLC Column

SUPELCOSIL™ LC-NH2 HPLC Column

More from Merck.

CombiTitrant 5

SUPELCOSIL™ ABZ+Plus HPLC Column

SUPELCOSIL™ LC-CN HPLC Column

SUPELCOSIL™ LC-NH2 HPLC Column