Description
General description
Mitochondria are organelles found in large numbers in most cells, in which the biochemical processes of respiration and energy production occurs. In metabolically active cells, mitochondria produce a membrane potential by maintaining a proton gradient across the inner and outer membranes. Loss of mitochondrial membrane potential is a hallmark for apoptosis and poor cell health.
BioTracker Mitochondria dyes are fluorogenic stains for staining mitochondria in live cells. The dyes are membrane permeable and become brightly fluorescent upon accumulation in the mitochondrial membrane. Staining is lost when mitochondria become depolarized during cell death, allowing monitoring of cell viability.
The BioTracker 633 Red Mitochondria Dye can be detected using the red Cy5 channel. The fluorescence is dependent on mitochondrial membrane potential, and the dye can be used to monitor changes in mitochondrial membrane potential in cells during apoptosis.
Spectral Properties
Absorbance: 622nm
Emission: 648nm
Application
Live cell fluorescent imaging
Live cell imaging mitochondrial dye that stains the membrane of mitochondria used to detect cell viability, metabolic activity and overall cell health.
Research Category
Cell Imaging
Research Sub Category
Live Cell Dye
Physical form
Lyophilized
Analysis Note
Spectral Properties
Absorbance: 622nm
Emission: 648nm
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
