Description
General description
This perylene derivative containing oligooxyethylene is designed for the detection of lipid peroxides. SCT260 emits intense fluorescence by lipid peroxide-specific oxidation in organic solvents such as ethanol. Among fluorescent probes that detect Reactive Oxygen Species(ROS), SCT260 is the only compound that can specifically detect lipid peroxides. Because the excitation and emission wavelengths of the oxidized probe are 524 nm and 535 nm, respectively, phototoxicity to and autofluorescence from the sample can be minimized. The tetraethyleneglycol group linked to one end of diisoquinoline ring enhances solubility and dispersibility in aqueous buffer.
This perylene derivative probe containing oligooxyethylene is designed for detection of lipid peroxides. BioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator emits intense fluorescence by lipid peroxide specific oxidation in organic solvents such as ethanol. This is the only RUO probe that can specifically detect lipid peroxides.SCT260′s oxidized form is nearly nonfluorescent in an aqueous media, but produces a bright fluorescence in lipophilic sites such as in cell membranes.This probe is light-sensitive, and should be pipetted as quickly as possible, preferably within one minute. Protect working solutions and samples from light, and use within one day of preparing working solution.
Features and Benefits
This perylene derivative probe containing oligooxyethylene is designed for the detection of lipid peroxides in live cells.
Preparation Note
Store BioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator at 2 - 8 °C, protected from light.
Other Notes
Live cell probe for fluorescent detection of lipid peroxidation by fluorescence microscopy or flow cytometry. SCT260 is a valuable reagent for ferroptosis research.
Legal Information
BioTracker is a trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
