Merck, SML2680-5MG, ES24

Name: ES24
Brand: Merck
SKU: SML2680-5MG

Size:5 mg, 2-{2-[3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazino}-2-oxoethylbenzene, ≥98% (HPLC)

Available Catalog Numbers

SML2680-25MG SML2680-5MG

Catalog Number: SML2680-5MG

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Category

Size Exclusion Resins

Pack Size5 mg

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

Biochem/physiol Actions
ES24 is an Eeyarestatin 1 analog that blocks protein translocation in vitro and more effectively enhances Sec61-mediated Ca²⁺ leakage from Endoplasmic Reticulum (ER). Apparently ES24 keep Sec61 in open position allowing Ca²⁺ ions to move freely through the aqueous channel present. It causes cell-type-specific Ca²⁺-dependent cell death.
blocks protein translocation in vitro and effectively enhances Sec61-mediated Ca²⁺ leakage from Endoplasmic Reticulum (ER).

Specifications

General

NACRES	NA.77
UNSPSC Code	12352200
assay	≥98% (HPLC)
form	powder
color	faint yellow to dark orange
solubility	DMSO: 2 mg/mL, clear
storage temp.	−20°C
Quality Level	100

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