Merck, SRP6201-50UG, Amphiregulin human

Name: Amphiregulin human
Brand: Merck
SKU: SRP6201-50UG

Size:50 μg, AR, AREG, Colorectum cell-derived growth factor (CRDGF), recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Available Catalog Numbers

SRP6201-10UG SRP6201-50UG

Catalog Number: SRP6201-50UG

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Category

Growth Factors & Cytokines

Pack Size50 µg

TagsCell Culture & Analysis Cell Culture Supplements & Reagents Growth Factors & Cytokines

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, amphiregulin′s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues.
Physical form
Sterile filtered through a 0.2 micron filter. Lyophilized from 5 mM Sodium phosphate, pH 7.0.
Preparation Note
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Specifications

General

NACRES	NA.32
UNSPSC Code	12352202
biological source	human
recombinant	expressed in E. coli
assay	≥95% (SDS-PAGE)
form	lyophilized powder
mol wt	11.3 kDa
packaging	pkg of 10 μg
UniProt accession no.	P15514
shipped in	wet ice
storage temp.	−20°C
Gene Information	human ... AREG(374)

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