Merck, TOX8-1KT, In Vitro Toxicology Assay Kit, Resazurin based

General description
In Vitro Toxicology Assay Kit (Resazurin based) is designed for fluorometrically or spectrophotometrically determining cell number as a function of metabolic activity using the dye resazurin. The resazurin method is simple, accurate, and reproducible
Application
In Vitro Toxicology Assay Kit, Resazurin based has been used:
in cell viability assay of human primary fibroblasts
to determine the cell proliferation rate in murine pre-osteoblasts
to determine the metabolic activity of microfluidic and monolayer cultures

Biochem/physiol Actions
Bioreduction of the dye reduces the amount of its oxidized form (blue) and concomitantly increases the fluorescent intermediate (red).