Merck, Y0001572, Atovaquone

Name: Atovaquone
Brand: Merck
SKU: Y0001572

Size:270 mg, Mepron, trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1, 4-naphthalenedione, European Pharmacopoeia (EP) Reference Standard

Catalog Number: Y0001572

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Category

pH Standards

Pack Size270 mg

TagsAnalytical Chemistry Reference Materials Pharma Standards

CollectionsMerck Certified Reference Materials: CRMs for Calibration, QC & Instrument Validation Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Atovaquone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions
Atovaquone in an anti-protozoal mitochondrial electron transport inhibitor. It also functions as an antimalarial and antipneumocystic agent.
Atovaquone is an anti-protozoal mitochondrial electron transport inhibitor; Antimalarial; Antipneumocystic, and has also been used to treat toxoplasmosis. It is an analog of protozoan mitochondrial protein ubiquinone, and acts by inhibiting the cytochrome bc(1) complex via interactions with the Rieske iron-sulfur protein and cytochrome b in the ubiquinol oxidation pocket.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.

Specifications

General

NACRES	NA.24
UNSPSC Code	41116107
InChI	1S/C22H19ClO3/c23-16-11-9-14(10-12-16)13-5-7-15(8-6-13)19-20(24)17-3-1-2-4-18(17)21(25)22(19)26/h1-4,9-13,15,26H,5-8H2/t13-,15-
InChI key	KUCQYCKVKVOKAY-CTYIDZIISA-N
SMILES string	OC1=C([C@H]2CC[C@@H](CC2)c3ccc(Cl)cc3)C(=O)c4ccccc4C1=O
grade	pharmaceutical primary standard
API family	atovaquone
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
format	neat
storage temp.	2-8°C

Ordering

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Merck, Y0001572, Atovaquone

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General

Notice

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