Promega, G7231, Caspase Inhibitor Z-VAD-FMK

Name: Caspase Inhibitor Z-VAD-FMK
Brand: Promega
SKU: G7231

Catalog Number: G7231

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Category

Apoptosis Detection Kits

TagsApoptosis Assays Cell Health Assays

Description

Z-VAD-FMK (carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]-fluoromethylketone) is a cell-permeant pan caspase inhibitor that irreversibly binds to the catalytic site of caspase proteases and can inhibit induction of apoptosis. For inhibition of apoptosis, Z-VAD-FMK should be added at the same time that apoptosis is induced. Z-VAD-FMK is provided at 20mM in DMSO for convenient addition to cell culture or extracts. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. The suggested concentration for use in the anti-Fas mAb-treated Jurkat cell culture model system is 20μM.
For more information, see the Protocols & Applications Guide .

Specifications

General

Catalog Number	G7231

Ordering

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