Description
Advantages
Prequalified According to ICH Guidelines: The bioassays demonstrate the precision, accuracy and linearity required for routine use in potency and stability studies.
Simple and Robust Workflow: Easy to implement with no specialized skills or training required.
Amenable to antibody screening and drug discovery: Run the bioassay in 96-well and 384-well plate formats.
Convenient Product Formats: Choose the product format that meets your experimental and workflow needs.
Applications
Demonstrate the activity and specificity of anti-CD3 bispecific antibodies.
Measure bispecific antibody potency and stability.
Determine the activity of CAR-T cell receptors.
Measure neutralizing antibody activity.
Available in a variety of convenient product formats.
Product Components and Format
The T Cell Activation Bioassay Kits include the following components: TCR/CD3 Effector Cells (NFAT or IL-2), Cell Culture Medium, Assay Reagents
The kits are available in 1 × components (1X) and 5 × components (5X) options.
The T Cell Activation Bioassay is also available in CPM format, containing cryopreserved cells that can be thawed, propagated and banked for long-term use. Bio-Glo™ Luciferase Assay System (Cat.# G7940, G7941) is the required reagent for use with T Cell Activation Bioassay, Propagation Model.
