Description
Study Proteins in Their Natural Cellular Context
NanoBRET® Transcriptional Protein Assays are sensitive, reproducible live-cell assays designed for monitoring or screening the interaction of proteins involved in transcriptional regulation. Interactions between proteins are key events in the regulation of gene expression with protein homodimers and heterodimers interacting on DNA elements to regulate transcriptional events required for a variety of cellular responses. The NanoBRET® cMyc/MAX Interaction Assay measures the specific interaction between the human cMyc and MAX transcription factors within their natural cellular context. The cMyc/MAX heterodimer regulates transcription related to cell proliferation, differentiation and apoptosis, making it an important candidate for drug targeting.
