Proteintech, 22305-1-AP-50uL, Amylin Polyclonal antibody

22305-1-AP targets Amylin in IHC, ELISA applications and shows reactivity with human, rat, mouse samples.
Background Information
IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring a tumor of the pancreas that is derived from beta cells and secretes INS. IAPP is co-secreted with INS by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.