Thermo Fisher, 27-1723-04, PAC-dA Phosphoramidite, standard grade, serum vial bottle

Quantity: 1 g
Unit Size: Each
PAC-dA CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyadenosine (dA) with Phenoxyacetyl (PAC) base protection, for use in oligonucleotide synthesis. The UltraMILD monomers - phenoxyacetyl (PAC)-dA, acetyl (Ac)-dC, and iso-propyl-phenoxyacetyl (iPr-PAC)-dG - were developed to alleviate the problem of modifiers and labels not withstanding prolonged exposure to strongly alkaline deprotection conditions. Cleavage and deprotection can be achieved in 4 hours at room temperature with 0.05M potassium carbonate in methanol. The 'Standard Grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20 mL Amber bottle with a Serum Vial neck style, which is compatible with most ABI Systems|AKTA Systems of oligonucleotide synthesizers. Features:• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite• Molecular formula: C_48H_54N_7O_8P• Base: dA• Base Protection: PAC• Formula weight: 887.96 g/mol• CAS number: 110543-74-3• HPLC Purity: ≥98.0%• ^31P NMR Purity: ≥98.0%