| Column Format | Analytical Column |
|---|---|
| Column Type | Reversed Phase |
| Endcapped | Yes |
| For Use With | LC/MS |
| Packing Material | Silica |
| Stationary Phase | C18 |
| Surface Area | 310 m²/g |
| USP Type | L1 |
| Carbon Load | 12% |
| Diameter (Metric) | 4.6 mm |
| Length (Metric) | 250 mm |
| Particle Size | 5 μm |
| Phase | Reversed Phase |
| Pore Size | 100 Å |
| pH | 2 to 8 |
| Unit Size | Each |
Answer:Yes. The polar-endcapped C18 phase is designed for compatibility with fully aqueous mobile phases.
Answer:The column measures 250 × 4.6 mm and contains 5 µm silica particles with 100 Å pores.
Answer:The polar endcapping modifies stationary-phase interactions and provides alternative selectivity, particularly under highly aqueous conditions.
Thermo Scientific Aquasil C18 is an analytical reversed-phase HPLC column with 5 µm silica particles, 100 Å pores and polar endcapping. Its 250 × 4.6 mm format combines hydrophobic C18 retention with an alternative selectivity profile compared with conventional endcapped C18 columns. The polar endcapping supports operation with highly aqueous mobile phases, including 100% aqueous conditions. The column has a 12% carbon load and is specified for pH 2–8. It is suitable for liquid chromatography methods that require aqueous compatibility without changing to an ion-exchange stationary phase.
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