Description
Quantity: 25 mL
Unit Size: Each
Features of POROS CaptureSelect AAVX resin include:
• One-step AAV purification from crude material with high purity and yield
• High specificity and capacity, maximizing yield by significantly reducing process steps
• Superior capacity maintained at high flow rates
• Excellent scalability and easier handling and packing due to rigid polymeric bead
• Non-animal derivedPOROS CaptureSelect AAVX Affinity Resin enables a robust, fast, and platformable purification process for wide-ranging AAV serotypes with excellent purity and yield obtained in one step. This resin comes with complete technical and regulatory support.Main characteristics
• Matrix:cross-linked poly(styrene-divinylbenzene) POROS beads
• Average particle size:50 μm
• Ligand:CaptureSelect AAVX affinity ligand
• Binding capacity:>1 x 10^13genome copies/mL of resin
• Elution conditions:acidic elution with 0.1 M glycine, pH 3.0
• Mechanical resistance:100 bar (1450 psi; 10 MPa)
• Formulation buffer:18% (v/v) ethanolFree of animal componentsCaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
