Thermo Fisher, J60422.14, Doxycycline hydrochloride

Name: Doxycycline hydrochloride
Brand: Thermo Fisher
SKU: J60422.14

Quantity: 25 g, Unit Size: Each, This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Suitable for battery materials development.

Catalog Number: J60422.14

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Category

Protein-Free Media

Pack Size25 g

TagsCell Culture Media Antibiotics Supplements and Reagents Cell Culture Reagents Antibiotics and Supplements

CollectionsThermo Fisher Cell Culture Media & Supplements | Serum-Free, Chemically Defined Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 25 g
Unit Size: Each
General Description
• Doxycycline hydrochloride is a compound that shows antibacterial and antimicrobial activities against several species, including Pseudomonas aeruginosa, Plasmodium falciparum, and Escherichia coli. It is also a bacteriostatic
• It can block the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesisApplication
• It is used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and eliminate Ixodes scapularis ticks
• Doxycycline hydrochloride is also considered to be a broad-spectrum inhibitor used to inhibit matrix metalloproteinases (MMP), such as type 1 collagenase, in wound healing and tissue remodeling studies. Due to this activity, it can inhibit angiogenesis and reduce lung metastases

Specifications

General

CAS	10592-13-9
Chemical Name or Material	Doxycycline hydrochloride
EINECS Number	234-198-7
Formula Weight	480.9
Health Hazard 1	H302+H312+H332-H315-H319-H335
Health Hazard 2	<b>GHS H Statement</b><br />H302-H315-H319-H335<br /> Harmful if swallowed.<br />Causes skin irritation.<br />Causes serious eye irritation.<br />May cause respiratory irritation.
Health Hazard 3	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
IUPAC Name	(1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride
InChI Key	VLUQVUWDECWBTL-UQVCFKGQSA-N
MDL Number	MFCD03427564
Melting Point	195°C to 201°C
Molecular Formula	C22H25ClN2O8
PubChem CID	54706018
Recommended Storage	Keep cold
SMILES	[Cl-].C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H]([NH+](C)C)C(=O)\C(=C(/N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12
Solubility Information	Soluble in water to 50mg/ml; May require warming.

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Thermo Fisher, J60422.14, Doxycycline hydrochloride

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