Thermo Fisher, 4405673, 3500 Genetic Analyzer

The Applied Biosystems 3500 Genetic Analyzer is an eight-capillary electrophoresis instrument for Sanger DNA sequencing and fluorescent fragment analysis. The 3500 platform separates labeled DNA fragments in parallel and detects fluorescent signals for downstream sequence calling, genotyping and fragment sizing. The configured system includes the eight-capillary instrument, 3500 Series Data Collection Software and a workstation with monitor. Its workflow is applicable to sequence confirmation, genetic marker analysis and identity testing in laboratories requiring controlled electrophoretic data collection. Appropriate chemistry, capillary arrays, polymer, buffers and analysis software are selected separately for the assay and existing laboratory configuration. The number of capillaries affects sample throughput but does not by itself determine the length or quality of a sequence read. Laboratory installation planning should account for space, computer/software compatibility, maintenance access and qualification needs. The 3500 is an analytical instrument rather than a sequencing reagent kit.