Thermo Fisher, M12414, MANT-GDP (2'-(or-3')-<i>O</i>-(<i>N</i>-Methylanthraniloyl) Guanosine 5'-Diphosphate, Disodium Salt)

Quantity: 400 μL
Unit Size: Each
The nucleotide analog MANT GDP is modified on the ribose moiety. The compact mature of the MANT fluorophore and its attachment position results in nucleotide analogs that induce minimal perturbation of nucleotide-protein interactions. Because MANT fluorescence is sensitive to the environment of the fluorophore, nucleotide-protein interactions may be directly detectable. MANT nucleotides are valuable probes of the structure and enzymatic activity of nucleotide-binding proteins.Drug Discovery and Development, Enzyme and Protein Activity Assays, Phosphatase Activity, Phosphatase Biology, Proteins, Expression, Isolation and Analysis, Target and Lead Identification and Validation