Tosoh, 0022853, TOYOPEARL DEAE-650C

TOYOPEARL DEAE-650C resin is a weak anion exchanger for biomolecule purification. The resin is composed of a base material of hydroxylated methacrylic polymer beads that have been functionalized with diethylaminoethyl (DEAE) weak anion exchange groups. TOYOPEARL DEAE-650C has a high degree of chemical and mechanical stability, allowing cleaning-in-place (CIP) and very high flow rates. TOYOPEARL DEAE-650C has a 100 nm pore size and a 100 µm bead size and can be used for high throughput capture, intermediate purification, and polishing process steps. If greater resolution is needed, the smaller particle TOYOPEARL DEAE-650M, TOYOPEARL DEAE-650S, or TSKgel DEAE-5PW resins may be used. As both the TOYOPEARL DEAE-650 and TSKgel DEAE-5PW resins use the same ligand and backbone chemistry, the selectivity between the two resin types will be unchanged.