Tosoh, 0023440, TOYOPEARL NH2-750F

TOYOPEARL NH2-750F media is a salt tolerant anion exchange resin capable of aggregate removal in both flow-through and binding and elution modes. The resin is composed of a base material of hydroxylated methacrylic polymer beads that have been functionalized with proprietary primary amine (NH 2 ) strong anion exchange groups. TOYOPEARL NH2-750F resin is ideal for process scale applications from the capture of proteins from biological feedstock (mammalian cell culture, plasma, bacterial feedstock, etc.) without dilution to the intermediate or final purification of monoclonal antibodies (mAbs) where aggregates and other impurities are removed from the target of interest. TOYOPEARL NH2-750F resin is available in one particle size, 45 µm, which corresponds to the F-grade designation. TOYOPEARL NH2-750F exhibits typical binding capacities in the vicinity of 70 g/L for BSA, maintains high capacity at increased linear velocities, has good pressure-flow characteristics, and will withstand back pressures up to 0.3 MPa .