Waters, 186001342, Atlantis dC18 Column, 100Å, 3 µm, 4.6 mm X 150 mm, 1/pk

Atlantis dC18 Column, 100Å, 3 µm, 4.6 mm X 150 mm, 1/pk is used for reversed-phase HPLC separations that need stronger retention of polar compounds while remaining compatible with highly aqueous mobile phases. The column uses a silica substrate with difunctionally bonded dC18 ligands and an endcapped surface. Its 3 µm spherical particles have a 100 Å pore size, and the phase carries a 12% carbon load. The 4.6 mm inner diameter × 150 mm format supports conventional analytical HPLC, with a maximum pressure of 6000 psi (415 bar) and a pH range of 3–7. The dC18 chemistry is optimized for aqueous conditions, including operation with 100% water, and is designed to resist dewetting while improving retention of polar analytes compared with conventional reversed-phase materials. This makes it useful for methods that must retain both polar and non-polar compounds without moving to a different separation mode. The 3 µm particle size provides a higher-efficiency format than standard 5 µm columns while preserving familiar 4.6 mm HPLC dimensions for routine method development and analytical testing.