Description
Key facts
CAS number:826-39-1,
Form:SolidSee storage information,
Molecular weight:203.75 Da,
Molecular formula:C11H22ClN,
PubChem:13221,
Nature:Synthetic,
Solubility:Soluble in water to 100 mMSoluble in DMSO to 75 mM,
Biochemical name:Mecamylamine hydrochloride,
Biological description:Non-competitive, non-selective antagonist of nicotinic actelycholine receptors (nAChRs). Blood-brain barrier permeable. Blocks various different nAChR types, (IC50 values are 640 nM, 2.5 μM, 3.6 μM and 6.9 μM at α3β4, α4β2, α3β2 and α7 receptors, respectively). Blocks most physiological, behavioural and reinforcing effects of nicotine. Displays antidepressant-like effects in mice.,
Canonical smiles:CC1(C2CCC(C2)C1(C)NC)C.Cl,
InChi:InChI=1S/C11H21N.ClH/c1-10(2)8-5-6-9(7-8)11(10,3)12-4;/h8-9,12H,5-7H2,1-4H3;1H,
InChiKey:PKVZBNCYEICAQP-UHFFFAOYSA-N,
IUPAC Name:N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine;hydrochloride
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
