Abcam, ab120979-10mg, Ro 67-4853, Positive allosteric modulator of mGlu1
MW 325.36 g/mol, Purity >99%. Potent, selective positive allosteric modulator for mGlu 1 (pEC 50 = 7.16 for rat mGlu 1a receptors). Increases basal mGluR 1 -induced cAMP accumulation and potentiates glutamate-induced cAMP accumulation. Selectively enhanced responses to DHPG in vivo ( EC 50 = 95 nM in CA3 neurons).
Available Catalog Numbers
Catalog Number: ab120979-10mg
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Pack Size10 mg
