Description
Key facts
CAS number:257933-82-7,
Purity:>97%,
Form:SolidSee storage information,
Molecular weight:467.9 Da,
Molecular formula:C24H23ClFN5O2,
PubChem:6445562,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mM,
Biochemical name:Pelitinib,
Biological description:Irreversible EGFR inhibitor (IC50 = 38.5 nM). Greater inhibitory activity against EGFR then erbB-2, Src, Cdk4, c-Met, Raf, MEK/ERK (IC50 values are 1255, 282, >20,000, 4100, 3353 and 800 nM respectively). Active in vivo.,
Canonical smiles:CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)F)Cl)C#N)NC(=O)C=CCN(C)C,
Isomeric smiles:CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)F)Cl)C#N)NC(=O)/C=C/CN(C)C,
InChi:InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+,
InChiKey:WVUNYSQLFKLYNI-AATRIKPKSA-N,
IUPAC Name:(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
