Abcam, ab141930-100mg, Erlotinib hydrochloride, EGFR tyrosine kinase inhibitor

Key facts
CAS number:183319-69-9,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:429.9 Da,
Molecular formula:C22H24ClN3O4,
PubChem:176871,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM (with warming),
Biochemical name:Erlotinib hydrochloride,
Biological description:Potent EGFR tyrosine kinase inhibitor (IC50 = 2 nM). Decreases EGFR autophosphorylation in tumor cells. Potent inhibitor of mutant JAK2-V617F. Weaker inhibitor of ErbB-2 kinase (Ki = 1 μM) and ErbB-4 kinase (Ki = 1.5 μM). Clinically effective agent for non-small cell lung cancer (NSCLC).,
Canonical smiles:COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl,
InChi:InChI=1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H,
InChiKey:GTTBEUCJPZQMDZ-UHFFFAOYSA-N,
IUPAC Name:N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions