Description
Key facts
CAS number:3519-82-2,
Purity:>97%,
Form:SolidSee storage information,
Molecular weight:284.31 g/mol,
Molecular formula:C20H12O2,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM,
Biological description:Potent, cell-permeable, selective calcineurin-NFAT interaction inhibitor (Kd = 800 nM). Blocks NFAT dephosphorylation, cytokine mRNA induction and nuclear import (~40 μM). Unlike CsA (ab120114) and FK506 (ab120223) INCA-6 does not indiscriminately block other calcineurin substrates. Anti-inflammatory agent. Active in vitro and in vivo.,
Canonical smiles:C1=CC=C2C3C4=CC=CC=C4C(C2=C1)C5=C3C(=O)C=CC5=O,
InChi:InChI=1S/C20H12O2/c21-15-9-10-16(22)20-18-12-6-2-1-5-11(12)17(19(15)20)13-7-3-4-8-14(13)18/h1-10,17-18H,
InChiKey:GCHPUOHXXCNSQL-UHFFFAOYSA-N,
IUPAC Name:9,10-Dihydro-9,10[1',2']-benzenoanthracene-1,4-dione
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
