Description
Key facts
Form:SolidSee storage information,
Molecular weight:248.3 Da,
Molecular formula:C9H16N2O4S,
PubChem:53393934,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM,
Biochemical name:CID 53393934,
Biological description:Potent, selective O-GlcNAcase inhibitor (Ki = 21 nM). Blocks tau phosphorylation. Increases O-GlcNAc-modified protein levels (EC50 = 30 nM). Shows antitauopathic effects in vivo. Orally active. Blood-brain barrier permeable.,
Canonical smiles:CCNC1=NC2C(C(C(OC2S1)CO)O)O,
Isomeric smiles:CCNC1=NC2C(C(C(OC2S1)CO)O)O,
InChi:InChI=1S/C9H16N2O4S/c1-2-10-9-11-5-7(14)6(13)4(3-12)15-8(5)16-9/h4-8,12-14H,2-3H2,1H3,(H,10,11),
InChiKey:PPAIMZHKIXDJRN-UHFFFAOYSA-N,
IUPAC Name:2-(ethylamino)-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
