Abcam, ab146829-10mg, Compound 6877002, CD40-TRAF6 interaction inhibitor

Key facts
CAS number:433249-94-6,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:251.33 g/mol,
Molecular formula:C17H17NO,
Nature:Synthetic,
Solubility:Soluble in ethanol to 100 mMSoluble in DMSO to 100mM,
Biological description:CD40-TRAF6 interaction inhibitor. Small molecule that binds to TRAF6, blocking interactions with CD40. Suppresses CD40-induced IL-1β and IL-6 expression in primary macrophages in vitro. Improves insulin sensitivity, reduces adipose tissue inflammation, and ameliorates hepatosteatosis in a mouse diet-induced obesity model.,
Isomeric smiles:CC2CC(N/C=C/C(=O)C1CCCCC1)C(C)CC2,
InChi:InChI=1/C17H17NO/c1-13-8-9-14(2)16(12-13)18-11-10-17(19)15-6-4-3-5-7-15/h3-12,18H,1-2H3/b11-10+,
InChiKey:SARYOFMRLSHZFE-ZHACJKMWNA-N,
IUPAC Name:3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C