Key facts
CAS number:169939-93-9,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:505 Da,
Molecular formula:C28H29ClN4O3,
PubChem:9870785,
Nature:Synthetic,
Solubility:Soluble in DMSO to 20 mM,
Biochemical name:Ruboxistaurin Hydrochloride,
Biological description:Potent, isozyme-selective inhibitor of protein kinase Cβ (PKCβ). Competitively inhibits PKCßI and PKCßII (IC50 values are 4.7 and 5.9 nM respectively). 76- and 61-fold selective for inhibition of PKCßI and PKCßII in comparison to PKCα, respectively. Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).,
Canonical smiles:CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl,
Isomeric smiles:CN(C)C[C@@H]1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl,
InChi:InChI=1S/C28H28N4O3.ClH/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24;/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34);1H/t18-;/m0./s1,
InChiKey:NYQIEYDJYFVLPO-FERBBOLQSA-N,
IUPAC Name:(18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-dione;hydrochloride
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2156 LY-333,531 hydrochloride. 2156-250 is the same size as the 250 µg size of ab219866.
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions
