Description
Key facts
CAS number:1313881-70-7,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:432.5 Da,
Molecular formula:C27H24N6,
PubChem:53262401,
Nature:Synthetic,
Solubility:Soluble in DMSO to 159.92 mMSoluble in ethanol to 8.52 mM,
Biochemical name:Miransertib,
Biological description:Allosteric, selective, non-ATP competitive pan-Akt inhibitor (IC50 = 5.0, 4.5, and 16 nM for Akt1, Akt2, and Akt3, respectively). Selective for Akt isoforms over a panel of 303 other kinases. Binds to and inhibits the activity of AKT in a non-ATP competitive manner, which may result in the inhibition of the PI3K/AKT signaling pathway. Orally bioavailable.,
Canonical smiles:C1CC(C1)(C2=CC=C(C=C2)N3C4=C(C=CC(=N4)C5=CC=CC=C5)N=C3C6=C(N=CC=C6)N)N,
InChi:InChI=1S/C27H24N6/c28-24-21(8-4-17-30-24)25-32-23-14-13-22(18-6-2-1-3-7-18)31-26(23)33(25)20-11-9-19(10-12-20)27(29)15-5-16-27/h1-4,6-14,17H,5,15-16,29H2,(H2,28,30),
InChiKey:HNFMVVHMKGFCMB-UHFFFAOYSA-N,
IUPAC Name:3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenylimidazo[4,5-b]pyridin-2-yl]pyridin-2-amine
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B1931 Miransertib. B1931-25 is the same size as the 25 mg size of ab235550.
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions
