Description
Key facts
CAS number:491833-30-8,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:418.6 Da,
Molecular formula:C24H38N2O4,
PubChem:23652732,
Nature:Synthetic,
Solubility:DMSO,
Biochemical name:Genz-123346 free base,
Biological description:Potent and selective glucosylceramide synthase inhibitor with potential anticancer activity.Does not affect the activities of other related glycosidase, such as 1-Oacylceramide synthase, a-glucosidase, and glucocerebrosidase in any significant manner.Shown to improve glucose tolerance, improve insulin sensitivity, and normalize hemoglobin A1C levels in Zucker diabetic fatty rats.,
Canonical smiles:CCCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O,
Isomeric smiles:CCCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O,
InChi:InChI=1S/C24H38N2O4/c1-2-3-4-5-6-7-10-23(27)25-20(18-26-13-8-9-14-26)24(28)19-11-12-21-22(17-19)30-16-15-29-21/h11-12,17,20,24,28H,2-10,13-16,18H2,1H3,(H,25,27)/t20-,24-/m1/s1,
InChiKey:JMNXWOFCUJJYEO-HYBUGGRVSA-N,
IUPAC Name:N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]nonanamide
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2286 genz-123346. B2286-10 is the same size as the 10 mg size of ab286986.
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
