Description
Key facts
CAS number:846557-71-9,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:511.6 Da,
Molecular formula:C29H25N3O4S,
PubChem:1383822,
Nature:Synthetic,
Solubility:>25 mg/ml in DMSO,
Biochemical name:2-(1,3-benzodioxol-5-yl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide,
Biological description:A potent and selective Nrf2 inhibitor (Nrf2; IC50 = 1.9 μM). ML-385 blocks Nrf2 downstream target gene expression. ML-385 displays specificity and selectivity for NSCLC cells with KEAP1 mutation, which leads to gain of Nrf2 function.,
Canonical smiles:CC1=CC=CC=C1C(=O)N2CCC3=C2C=CC(=C3)C4=C(SC(=N4)NC(=O)CC5=CC6=C(C=C5)OCO6)C,
InChi:InChI=1S/C29H25N3O4S/c1-17-5-3-4-6-22(17)28(34)32-12-11-20-15-21(8-9-23(20)32)27-18(2)37-29(31-27)30-26(33)14-19-7-10-24-25(13-19)36-16-35-24/h3-10,13,15H,11-12,14,16H2,1-2H3,(H,30,31,33),
InChiKey:LINHYWKZVCNAMQ-UHFFFAOYSA-N,
IUPAC Name:2-(1,3-benzodioxol-5-yl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2605 ML-385. B2605-25 is the same size as the 25 mg size of ab287109.
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark
