Biolegend, 150325, Alexa Fluor® 488 anti-mouse CD198 (CCR8) Antibody
25microg
Catalog Number: 150325
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Category
| Verified Reactivity | Mouse |
|---|---|
| Antibody Type | Monoclonal |
| Host Species | Rat |
| Immunogen | Mouse CD198 (CCR8)-transfected cells |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions. |
| Concentration | 0.5 mg/mL |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
| Excitation Laser | Blue Laser (488 nm) |
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| RRID |
|---|
| AB_2890697 (BioLegend Cat. No. 150325) AB_2890697 (BioLegend Cat. No. 150326) |
| Structure | G-protein coupled receptor, 7 transmembrane regions, 41 kD. |
|---|
| Distribution | Thymocytes, Tregs, NKT and Th2-polarized cells, subset of macrophages, monocytes and monocyte-derived dendritic cells. |
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| Function | Chemotaxis, involved in thymocyte apoptosis |
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| Ligand/Receptor | CCL1 (SCY1,TCA-3) |
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| Cell Type | Dendritic cells, Macrophages, Monocytes, NKT cells, Th2, Thymocytes, Tregs |
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| Biology Area | Immunology |
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| Molecular Family | CD Molecules, Cytokine/Chemokine Receptors, GPCR |
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| Antigen References | 1. Coghill JM, et al. 2013. Blood. 122:825. 2. Islam SA, et al. 2011. Nat. Immunol. 12:167. 3. Hoshino A, et al. 2007. J. Immunol. 178:5296. 3. Qu C, et al. 2004. J. Exp. Med. 200:1231. |
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| Gene ID | 12776 |
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| UniProt | View information about CD198 on UniProt.org |
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| Clone | SA214G2 |
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| Regulatory Status | RUO |
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| Other Names | CDw198, C-C chemokine receptor type 8, CKR-8, CC-CKR-8, Ter1 |
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| Isotype | Rat IgG2b, κ |
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