Biolegend, 260508, GMP PE anti-human CD203c Antibody
100tests
Catalog Number: 260508
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| Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | HEK-293 cells transfected with human E-NPP3 |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA) and a stabilizer |
| Preparation | The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. |
| Concentration | 100 µg/mL |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Excitation Laser | Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm) |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
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| Application References(PubMed link indicates BioLegend citation) |
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| Bühring HJ, et al. 1999. Blood 94:2343. Bühring HJ, et al. 2001. Blood 97:3303. Platz IJ, et al. 2001. Int. Arch. Allergy Immunol. 126:335. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed Gernez Y, et al. 2011. Int. Arch. Allergy Immunol. 154:318. (FC) PubMed |
| Disclaimer | GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures. Our processes include: Batch-to-batch consistency Material traceability Documented procedures Documented employee training Equipment maintenance and monitoring records Lot-specific certificates of analysis Quality audits per ISO 13485:2016 QA review of released products |
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| Structure | Transmembrane ectoenzyme family member involved in the hydrolysis of extracellular oligonucleotides, nucleoside phosphates, and NAD (possesses ATPase and ATP pyrophosphatase activity); reduced molecular weight is 130 and 150 kD, unreduced is 270 kD |
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| Distribution | Basophils and mast cells, highly expressed on activated basophils; secretory glands in endometrium and glioma cells are also positive |
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| Function | Multifunctional ectoenzyme involved in the clearance of extracellular nucleotides |
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| Ligand/Receptor | Substrates include nucleoside triphosphates, nucleoside diphosphates, cAMP, and NAD |
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| Cell Type | Basophils, Mast cells |
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| Biology Area | Immunology |
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| Molecular Family | CD Molecules |
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| Antigen References | 1. Yano Y, et al. 2003. Int. J. Mol. Med. 12:763. 2. Andoh K, et al. 1999. Biochim. Biophys. Acta. 1446:213. |
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| Gene ID | 5169 |
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| UniProt | View information about CD203c on UniProt.org |
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| Clone | NP4D6 |
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| Workshop | HLDA8 |
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| Other Names | E-NPP3, ENPP3 |
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| Isotype | Mouse IgG1, κ |
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