Biolegend, 323212, Alexa Fluor® 647 anti-human CD105 Antibody
100tests
Catalog Number: 323212
Send an RFQ.
Category
Loading…
| Verified Reactivity | Human |
|---|---|
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | L-cells transfected with human CD105 |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:
Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.
| Excitation Laser | Red Laser (633 nm) |
|---|
| Application References(PubMed link indicates BioLegend citation) | Bühring HJ, et al. 1991. Leukemia 5:841. Vogel W, et al. 2002. Haematologica 88:126. Osaka M, et al. 2011. Brain Res. 9:1343. PubMed HonMou O, et al. 2011. Brain. 134:1790. PubMed Herrera MB, et al. 2013. Hepatology. 57:311. PubMed Iohara K, et al. 2014. Exp Gerontol. 52:39. PubMed |
|---|
| Product Citations | Slamecka J, et al. 2017. Cell Cycle. 17:330. PubMed Pasquier J, et al. 2018. Mol Cancer. 17:47. PubMed Gallouet A, et al. 2014. Clin Cancer Res. 20:2663. PubMed |
|---|
| RRID | AB_2099035 (BioLegend Cat. No. 323212) |
|---|
| Structure | Associates with TGF-ß receptor I and II, homodimeric type I integral membrane protein, 90 kD |
|---|
| Distribution | Endothelial cells, activated monocytes/macrophages, bone marrow stromal cells, hematopoietic stem/progenitor cells |
|---|
| Function | Modulates cellular response to TGF-ß, involved in vascular development and remodelling |
|---|
| Ligand/Receptor | TGF-ß1, TGF-ß3 |
|---|
| Cell Type | Endothelial cells, Hematopoietic stem and progenitors, Macrophages, Mesenchymal Stem Cells, Monocytes |
|---|
| Biology Area | Angiogenesis, Cell Biology, Immunology, Stem Cells |
|---|
| Molecular Family | Adhesion Molecules, CD Molecules |
|---|
| Antigen References | 1. Mason D, et al. Eds. 2002. Leucocyte Typing VII. Oxford University Press. New York. 2. Pierelli L, et al. 2001. Leuk. Lymphoma 42:1195. |
|---|
| Gene ID | 2022 |
|---|
| UniProt | View information about CD105 on UniProt.org |
|---|
| Clone | 43A3 |
|---|
| Regulatory Status | RUO |
|---|
| Other Names | Endoglin |
|---|
| Isotype | Mouse IgG1, κ |
|---|
