Biolegend, 326410, Alexa Fluor® 647 anti-human CD85g (ILT7) Antibody
100tests
Catalog Number: 326410
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Category
Pack Size85 g
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
| Excitation Laser |
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| Red Laser (633 nm) |
| Application Notes | Additional reported (for the relevant formats) applications include: trigger ILT7 mediated signaling.The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 326413 and 326414). |
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| Application References(PubMed link indicates BioLegend citation) | Jensen MA, et al. 2013. Ann Rheum Dis. 72:596. PubMed. |
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| Product Citations | Bego M, et al. 2015. PLoS Pathog. 11: 1005024. PubMed |
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| RRID | AB_2265747 (BioLegend Cat. No. 326410) |
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| Structure | Associate with FcεR1γ leukocyte immunoglobulin-like receptor gene family |
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| Distribution | Plasmacytoid dendritic cells |
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| Function | Negatively regulates pDC mediated innate immune function |
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| Cell Type | Dendritic cells |
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| Biology Area | Immunology, Innate Immunity |
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| Molecular Family | CD Molecules |
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| Antigen References | 1. Cao W, et al. 2006. J. Exp. Med. 203(6):1399. 2. Brown D, et al. 2004. Tissue Antigen. 64:215. 3. Rissoan MC, et al. 2002. Blood 100:3295. |
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| Gene ID | 23547 |
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| UniProt | View information about CD85g on UniProt.org |
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| Clone | 17G10.2 |
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| Regulatory Status | RUO |
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| Other Names | CD85g, immunoglobulin-like transcript 7, LILRA4 |
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| Isotype | Mouse IgG1, κ |
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