Biolegend, 339015, Purified anti-human CD122 (IL-2Rβ) (Maxpar® Ready) Antibody
100microg
Catalog Number: 339015
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| Verified Reactivity | Human |
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| Reported Reactivity | African Green, Baboon, Cynomolgus, Rhesus |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | TL-Mor cell line |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA. |
| Preparation | The antibody was purified by affinity chromatography. |
| Concentration | 1.0 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C. |
| Application | FC - Quality tested CyTOF® - Verified |
| Recommended Usage | This product is suitable for use with the Maxpar® Metal Labeling Kits. For metal labeling using Maxpar® Ready antibodies, proceed directly to the step to Partially Reduce the Antibody by adding 100 µl of Maxpar® Ready antibody to 100 µl of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar® User Guide when conjugating Maxpar® Ready antibodies. |
| Application Notes | Additional reported applications include (for the relevant formats) include: immunoprecipitation, blocking of IL-2 binding to CD122, and partial inhibition of IL-2 induced cell proliferation. |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
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| Additional Product Notes | Maxpar® is a registered trademark of Standard BioTools Inc. |
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| Application References(PubMed link indicates BioLegend citation) | Takeshita T, et al. 1989. J. Exp. Med. 169:1323. |
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| Product Citations | Labanieh L, et al. 2022. Cell. 185:1745. PubMed van Montfoort N, et al. 2018. Cell. 175:1744. PubMed |
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| RRID | AB_2563712 (BioLegend Cat. No. 339015) |
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| Structure | Ig superfamily, forms high affinity IL-2 receptor with CD25 and CD132 chains or intermediate affinity receptor with CD132 alone, 70-75 kD |
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| Distribution | NK cells, T subset |
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| Function | Critical component of IL-2 and IL-15 signaling |
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| Ligand/Receptor | IL-2, IL-15 |
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| Cell Type | NK cells, T cells, Tregs |
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| Biology Area | Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers |
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| Molecular Family | CD Molecules, Cytokine/Chemokine Receptors |
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| Antigen References | 1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication 2. Minami Y, et al. 1993. Annu. Rev. Immunol. 11:245. 3. Suzuki H, et al. 1995. Science 268:1472. |
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| Gene ID | 3560 |
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| UniProt | View information about CD122 on UniProt.org |
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| Clone | TU27 |
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| Regulatory Status | RUO |
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| Workshop | V C050 |
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| Other Names | IL-2 Receptor β chain, IL-2Rβ |
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| Isotype | Mouse IgG1, κ |
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