Biolegend, 342801, Alexa Fluor® 647 anti-human CD305 (LAIR1) Antibody
25tests
Catalog Number: 342801
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
| Excitation Laser |
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| Red Laser (633 nm) |
| Application References(PubMed link indicates BioLegend citation) | Poggi A, et al. 1995. Eur. J. Immunol. 25:369 |
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| Product Citations | van der Wijst MGP, et al. 2021. Sci Transl Med. 13:eabh2624. PubMed Seery V, et al. 2021. EBioMedicine. 67:103357. PubMed |
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| RRID | AB_1659239 (BioLegend Cat. No. 342801) AB_2133480 (BioLegend Cat. No. 342802) |
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| Structure | 40 kD type I transmembrane protein, cytoplasmic domain contains ITIM motifs, Ig superfamily |
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| Distribution | NK cells, T cell, B cells, monocytes, dendritic cells, eosinophils, basophils and mast cells |
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| Function | Inhibition of cell cytotoxicity, cell activation, proliferation and differentiation |
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| Ligand/Receptor | collagens |
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| Cell Type | B cells, Basophils, Dendritic cells, Eosinophils, Macrophages, Mast cells, Monocytes, NK cells, T cells |
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| Biology Area | Immunology, Inhibitory Molecules, Innate Immunity |
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| Molecular Family | CD Molecules |
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| Antigen References | 1. Meyaard L, et al. 2008. J. Leukoc. Biol. 83:799 2. Lebbink RJ, et al. 2006. J. Exp. Med. 203:1419 |
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| Gene ID | 3903 |
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| UniProt | View information about CD305 on UniProt.org |
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| Clone | NKTA255 |
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| Regulatory Status | RUO |
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| Workshop | HCDM listed |
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| Other Names | LAIR-1 (Leukocyte-associated Ig-like receptor 1) |
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| Isotype | Mouse IgG1, κ |
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