Biolegend, 350015, Purified anti-human CD134 (OX40) (Maxpar® Ready) Antibody
100microg
Catalog Number: 350015
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| Verified Reactivity | Human |
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| Reported Reactivity | Chimpanzee |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | HTLV 1-transformed HUT 102 cells |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA. |
| Preparation | The antibody was purified by affinity chromatography. |
| Concentration | 1.0 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C. |
| Application | FC - Quality tested CyTOF® - Verified |
| Recommended Usage | This product is suitable for use with the Maxpar® Metal Labeling Kits. For metal labeling using Maxpar® Ready antibodies, proceed directly to the step to Partially Reduce the Antibody by adding 100 µl of Maxpar® Ready antibody to 100 µl of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar® User Guide when conjugating Maxpar® Ready antibodies. |
| Application Notes | Additional reported applications (for the relevant formats) include: Western blotting1, immunoprecipitation1, immunohistochemical staining2,3of paraffin embedded7 and frozen tissue sections, ELISA4, and functional assay5. The LEAF™ or Ultra-LEAF™ purified antibody is recommended for functional assays (contact our custom solutions team). |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
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| Additional Product Notes | Maxpar® is a registered trademark of Standard BioTools Inc. |
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| Application References(PubMed link indicates BioLegend citation) | Latza U, et al. 1994. Eur. J. Immunol. 24:677. (WB, IP) Durkop H, et al. 1995. Brit. J. Haematol. 91:927. (IHC) Durkop H, et al. 1997. Brit. J. Haematol. 98:863. (IHC) Willett B, et al. 2007. J. Virol. 81:9665. (ELISA) Li M and Zhang Y. et al. 2005. Cell. Mol. Immunol. 2:467. (FA) Gloviczki ML, et al. 2012. Clin. J. Am. Soc. Nephrol. 8:546. PubMed Domingos PL, et al. 2012. An. Bras. Dermatol. 87:851. (IHC) |
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| Product Citations | Duraiswamy J, et al. 2021. Cancer Cell. 39:1623. PubMed Gide TN, et al. 2019. Cancer Cell. 35:238. PubMed |
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| RRID | AB_2563718 (BioLegend Cat. No. 350015) |
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| Structure | 50 kD, TNF receptor family |
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| Distribution | Activated T cells |
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| Function | Receptor for OX40 ligand, co-stimulatory signal for T cell proliferation and survival. |
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| Ligand/Receptor | OX40L (CD252) |
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| Cell Type | T cells, Tregs |
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| Biology Area | Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Costimulatory Molecules, Immunology |
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| Molecular Family | CD Molecules, Immune Checkpoint Receptors |
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| Antigen References | 1. Smith CA, et al. 1994. Cell. 76:959. 2. Chen AL, et al. 1999. Immunity. 11:689. 3. Croft M. 2010. Annu. Rev. Immunol. 28:57. 4. Withers DR, et al. 2009. J. Immunol. 183:5079. 5. Klinger M, et al. 2009. J. Immunol. 182:4581. |
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| Gene ID | 7293 |
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| UniProt | View information about CD134 on UniProt.org |
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| Clone | Ber-ACT35 (ACT35) |
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| Regulatory Status | RUO |
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| Other Names | ACT35 antigen, tumor necrosis factor receptor superfamily member 4 (TNFRSF4) |
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| Isotype | Mouse IgG1, κ |
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