Biolegend, 353237, Purified anti-human CD197 (CCR7) (Maxpar® Ready) Antibody
100microg
Catalog Number: 353237
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| Verified Reactivity | Human |
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| Reported Reactivity | African Green, Baboon, Cynomolgus, Rhesus |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | CCR7-transfected cells |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA. |
| Preparation | The antibody was purified by affinity chromatography. |
| Concentration | 1.0 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C. |
| Application | FC - Quality tested CyTOF® - Verified |
| Recommended Usage | This product is suitable for use with the Maxpar® Metal Labeling Kits. For metal labeling using Maxpar® Ready antibodies, proceed directly to the step to Partially Reduce the Antibody by adding 100 µl of Maxpar® Ready antibody to 100 µl of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar® User Guide when conjugating Maxpar® Ready antibodies. |
| Additional Product Notes | Maxpar® is a registered trademark of Standard BioTools Inc. |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
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| Product Citations |
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| Gide TN, et al. 2019. Cancer Cell. 35:238. PubMed Roussel M, et al. 2021. Cell Reports Medicine. 2(6):100291. PubMed Jordan S, et al. 2020. Cell. 178(5):1102-1114.e17.. PubMed Wimmers F, et al. 2021. Cell. 184:3915. PubMed |
| RRID | AB_2563726 (BioLegend Cat. No. 353237) |
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| Structure | Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor. |
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| Distribution | T cells, B cells, NK, dendritic cells. |
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| Function | The chemokine receptor CCR7 plays a pivotal role in the homing of naïve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels. |
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| Ligand/Receptor | CCL19 and CCL21. |
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| Cell Type | B cells, Dendritic cells, NK cells, T cells |
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| Biology Area | Immunology |
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| Molecular Family | CD Molecules, Cytokine/Chemokine Receptors, GPCR |
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| Antigen References | 1. Yanagihara S, et al. 1998. J. Immunol. 161:3096. 2. Charo IF, et al. 2006. N. Engl. J. Med. 354:610. 3. Reif K, et al. 2002. Nature 416:94. 4. Nakata B, et al. 2008. Oncology 74:69. 5. Brodie T. et al. 2013. Cytometry A. 6: 530-2. PubMed 6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9 PubMed 7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8 PubMed |
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| Gene ID | 1236 |
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| UniProt | View information about CD197 on UniProt.org |
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| Clone | G043H7 |
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| Regulatory Status | RUO |
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| Other Names | BLR2, CDw197, EBI1, CMKBR7 |
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| Isotype | Mouse IgG2a, κ |
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