Biolegend, 353621, Alexa Fluor® 647 anti-human CD371 (CLEC12A) Antibody
25tests
Catalog Number: 353621
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | 293T cells expressing CLEC12A-Flag |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
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| Excitation Laser | Red Laser (633 nm) |
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| Application References(PubMed link indicates BioLegend citation) | Lahoud MH, et al. 2009. J. Immunol. 182:7587. (FC) Lahoud MH, et al. 2011. J. Immunol. 187:842. (FC) Neumann K, et al. 2014. Immunity. 40:389. PubMed |
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| RRID | AB_2936772 (BioLegend Cat. No. 353621) AB_2936772 (BioLegend Cat. No. 353622) |
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| Structure | Type II C-type lectin family member, 265 aa, 30.7 kD |
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| Distribution | Monocytes, granulocytes, NK cells, and basophils |
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| Function | Negative regulator of granulocyte and monocyte function |
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| Interaction | PTPN6 and PTPN11 |
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| Cell Type | Basophils, Dendritic cells, Granulocytes, Monocytes, NK cells |
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| Biology Area | Costimulatory Molecules, Immunology |
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| Molecular Family | CD Molecules |
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| Antigen References | 1. Lahoud MH, et al. 2009. J. Immunol. 182:7587. 2. Chen CH, et al. 2006. Blood 107:1459. 3. Marshall AS, et al. 2004. J. Biol. Chem. 279:14792. |
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| Gene ID | 160364 |
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| UniProt | View information about CD371 on UniProt.org |
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| Clone | 50C1 |
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| Regulatory Status | RUO |
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| Workshop | HCDM listed |
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| Other Names | CLL1, MICL, CLL-1, DCAL-2, C-type lectin domain family 12 member A, CD371 |
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| Isotype | Mouse IgG2a, κ |
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