Biolegend, 353733, Purified anti-human CD183 (CXCR3) (Maxpar® Ready) Antibody
100microg
Catalog Number: 353733
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| Verified Reactivity | Human, Cynomolgus, Rhesus |
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| Reported Reactivity | African Green, Baboon |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Human CXCR3 transfectants |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA. |
| Preparation | The antibody was purified by affinity chromatography. |
| Concentration | 1.0 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C. |
| Application | FC - Quality tested CyTOF® - Verified |
| Recommended Usage | This product is suitable for use with the Maxpar® Metal Labeling Kits. For metal labeling using Maxpar® Ready antibodies, proceed directly to the step to Partially Reduce the Antibody by adding 100 µl of Maxpar® Ready antibody to 100 µl of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar® User Guide when conjugating Maxpar® Ready antibodies. |
| Additional Product Notes | Maxpar® is a registered trademark of Standard BioTools Inc. |
| Product Citations |
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| Roussel M, et al. 2021. Cell Reports Medicine. 2(6):100291. PubMed Jordan S, et al. 2020. Cell. 178(5):1102-1114.e17.. PubMed |
| RRID | AB_2563724 (BioLegend Cat. No. 353733) |
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| Structure | CXC-chemokine receptor, G protein-coupled receptor, seven-pass transmembrane receptor |
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| Distribution | T cell subset, NK cells, plasmacytoid dendritic cells, GM-CSF activated CD34+ hematopoietic progenitors, mast cells, alveolar macrophages, eosinophils, and airway epithelial cells |
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| Function | Essential in T cell recruitment to sites of inflammation |
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| Ligand/Receptor | CXCL9, CXCL10, and CXCL11 |
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| Cell Type | Dendritic cells, Eosinophils, Epithelial cells, Hematopoietic stem and progenitors, Macrophages, Mast cells, NK cells, T cells, Tregs |
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| Biology Area | Cell Biology, Immunology, Neuroinflammation, Neuroscience |
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| Molecular Family | CD Molecules, Cytokine/Chemokine Receptors, GPCR |
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| Antigen References | 1. Loetscher M, et al. 1996. J. Exp. Med. 184:963. 2. Cole KE, et al. 1998. J. Exp. Med. 187:2009. 3. Aksoy MO, et al. 2006. Am. J. Physiol. Lung Cell Mol. Physiol. 290:L909. 4. Curbishley SM, et al. 2005. Am. J. Pathol. 167:887. 5. Turner JE, et al. 2007. Mini. Rev. Med. Chem. 7:1089. 6. Wenzel J, et al. 2008. J. Invest. Dermatol. 128:67. |
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| Gene ID | 2833 |
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| UniProt | View information about CD183 on UniProt.org |
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| Clone | G025H7 |
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| Regulatory Status | RUO |
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| Other Names | CXCR3, G protein-coupled receptor 9 (GPR9), CKR-L2 |
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| Isotype | Mouse IgG1, κ |
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