Biolegend, 354215, Purified anti-human CD303 (BDCA-2) (Maxpar® Ready) Antibody
100microg
Catalog Number: 354215
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA. |
| Preparation | The antibody was purified by affinity chromatography. |
| Concentration | 1.0 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C. |
| Application | FC - Quality tested CyTOF® - Verified |
| Recommended Usage | This product is suitable for use with the Maxpar® Metal Labeling Kits. For metal labeling using Maxpar® Ready antibodies, proceed directly to the step to Partially Reduce the Antibody by adding 100 µl of Maxpar® Ready antibody to 100 µl of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar® User Guide when conjugating Maxpar® Ready antibodies. |
| Additional Product Notes | Maxpar® is a registered trademark of Standard BioTools Inc. |
| Application References(PubMed link indicates BioLegend citation) | Freeman A, et al. 2014. PLoS One. 9:110928. PubMed Johnson P, et al. 2015. Clin Cnacer Res. 21:1321. PubMed |
| Product Citations |
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| Gadalla R, et al. 2022. STAR Protoc. 3:101643. PubMed |
| RRID | AB_2563739 (BioLegend Cat. No. 354215) |
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| Structure | Type II transmembrane protein, 38 kD, member of the C-type lectin superfamily |
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| Distribution | Plasmacytoid dendritic cells |
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| Function | Antigen capture, inhibition of IFN α/β production |
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| Cell Type | Dendritic cells |
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| Biology Area | Costimulatory Molecules, Immunology, Innate Immunity |
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| Molecular Family | Adhesion Molecules, CD Molecules |
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| Antigen References | 1. Jähn PS, et al. 2010. Cell Immunol. 265:15. 2. Graham LM and Brown GD. 2009. Cytokine 48:148. 3. Röck J, et al. 2007. Eur. J. Immunol. 37:3564. 4. Dzionek A, et al. 2001. J. Exp. Med. 194:1823. |
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| Gene ID | 170482 |
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| UniProt | View information about CD303 on UniProt.org |
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| Clone | 201A |
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| Regulatory Status | RUO |
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| Other Names | CLEC4C, CLECSF11, CLECSF7, DLEC, HECL |
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| Isotype | Mouse IgG2a, κ |
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