Biolegend, 359404, Alexa Fluor® 647 anti-human CD194 (CCR4) Antibody
100tests
Catalog Number: 359404
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| Verified Reactivity | Human |
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| Reported Reactivity | Cynomolgus |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Human CCR4 transfected cells |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
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| Excitation Laser | Red Laser (633 nm) |
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| Product Citations | Yu X, et al. 2020. Front Immunol. 581180:11. PubMed Bhattacharya P, et al. 2020. Elife. 9:00. PubMed |
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| RRID | AB_2562388 (BioLegend Cat. No. 359403) AB_2562389 (BioLegend Cat. No. 359404) |
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| Structure | GPCR, seven transmembrane receptor |
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| Distribution | Expressed on a subset of T and B cells, basophils, monocytes, NK cells |
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| Function | Migration of inflammatory and regulatory cells to the target tissues |
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| Ligand/Receptor | CCL17 and CCL22 |
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| Cell Type | B cells, Basophils, Embryonic Stem Cells, Monocytes, NK cells, T cells, Tregs |
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| Biology Area | Immunology, Innate Immunity, Stem Cells |
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| Molecular Family | CD Molecules, Cytokine/Chemokine Receptors, GPCR |
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| Antigen References | 1. Katschke KJ, et al. 2001 Arthritis Rheum. 44:1022. 2. Colantonio L, et al. 2002 Eur. J. Immunol. 32:1264. 3. Jakubzick C et al. 2004 Am. J. Pathol. 165:1211. 4. Morimoto Y, et al. 2005 J. Leukoc. Biol. 78:753. 5. Baatar J, et al. 2007 J. Immunol. 178:4891. 6. Kusumoto M, et al. 2007 J. Interferon. Cytokine Res. 27:901. |
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| Gene ID | 1233 |
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| UniProt | View information about CD194 on UniProt.org |
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| Clone | L291H4 |
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| Regulatory Status | RUO |
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| Other Names | CKR4, K5-5, CMKBR4, ChemR13, CC-CKR-4, MGC88293, HGCN:14099 |
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| Isotype | Mouse IgG1, κ |
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