Biolegend, 362905, Alexa Fluor® 488 anti-human CD191 (CCR1) Antibody
25tests
Catalog Number: 362905
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Category
| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Human CCR1 transfected cells |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
Unless otherwise stated, the minimum order amount is USD 1,000.
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| Excitation Laser | Blue Laser (488 nm) |
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| Product Citations | Parrot T, et al. 2021. JCI Insight. 6:e140074. PubMed |
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| RRID | AB_2563916 (BioLegend Cat. No. 362905) AB_2563917 (BioLegend Cat. No. 362906) |
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| Structure | G-protein coupled receptor, seven transmembrane protein, 41 kD |
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| Distribution | Monocytes, macrophages, subset of T cells, eosinophils |
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| Function | Regulates migration of cells in response to CCL3 and CCL5 |
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| Ligand/Receptor | CCL3 and CCL5 |
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| Cell Type | Eosinophils, Macrophages, Monocytes, T cells |
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| Biology Area | Immunology |
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| Molecular Family | CD Molecules, Cytokine/Chemokine Receptors, GPCR |
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| Antigen References | 1. Su SB, et al. 1996. J. Leuko. Biol. 60:658. 2. Su S, et al. 1997. Blood. 90:605. 3. Ayehunie S, et al. 1997. Blood. 90:1379. 4. Gerard C, et al. 1997. J. Clin. Invest. 100:2022. 5. Tiffany HL, et al. 1998. J. Immunol. 160:1385. 6. Gilliland CT, et al. 2013. J. Biol. Chem. 288:32194. 7. Bednar F, et al. 2014. J. Immunol. 192:5305. |
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| Gene ID | 1230 |
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| UniProt | View information about CD191 on UniProt.org |
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| Clone | 5F10B29 |
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| Regulatory Status | RUO |
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| Other Names | CKR1, CD191, HM145, SCYAR1, CMKRB1 |
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| Isotype | Mouse IgG1, κ |
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