Biolegend, 368714, Alexa Fluor® 647 anti-human Cadherin 11 Antibody
100microg
Catalog Number: 368714
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Recombinant protein containing the extracellular cadherin domain 1 of Cadherin 11 fused to maltose binding protein. |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions. |
| Concentration | 0.5 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | IHC-P - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
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| Excitation Laser | Red Laser (633 nm) |
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| Application Notes | Additional reported applications (for the relevant formats) include: immunoprecipitation. |
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| RRID | AB_2721403 (BioLegend Cat. No. 368713) |
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| Structure | Type I single pass transmembrane glycoprotein. |
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| Distribution | Osteoblasts, neuroblasts, and some cancer cells. |
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| Function | Cell adhesion. |
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| Interaction | Cadherin 2 (CDH2). |
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| Ligand/Receptor | Calcium. |
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| Cell Type | Osteoclasts |
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| Biology Area | Cell Adhesion, Cell Biology, Immunology, Neuroscience, Synaptic Biology |
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| Molecular Family | Adhesion Molecules |
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| Antigen References | 1. Wheelock MJ, Johnson KR. 2003. Annu. Rev. Cell Dev. Biol. 19:207-35. 2. Christofori G, et al. 2003. EMBO. J. 22:2318. 3. Okazaki M, et al. 1994. J. Biol. Chem. 269:12092. |
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| Gene ID | 1009 |
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| UniProt | View information about Cadherin 11 on UniProt.org |
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| Clone | 16G5 |
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| Regulatory Status | RUO |
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| Other Names | OSF-4, Osteoblast cadherin, OB-cadherin, CDH11, CDHOB, CAD11 |
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| Isotype | Mouse IgG1, κ |
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